Preventive care: so many recommendations, so little time

So Many WAM Variations, So Little Time

So Many Zebras, So Little Time:

So many questions, so little time.

Fifteen years have elapsed since the first human infections with H5N1 highly pathogenic avian influenza (HPAI) virus were detected in Hong Kong SAR, China [1, 2]. Many of these human infections were fatal and represented the first documented outbreak of severe disease due to HPAI viruses. The hallmark of these H5N1 viruses is their hemagglutinin genes inherited from A/goose/Guangdong/1996, a vi...

Yeast two-hybrid: so many interactions, (in) so little time...

Protein-protein interactions are essential to cellular mechanisms at all levels in biologically responsive systems. These interactions occur extracellularly and include ligand-receptor interactions, cell adhesion, antigen recognition, and virus-host recognition. Intracellular protein-protein interactions occur in the formation of multi-protein complexes, during the assembly of cytoskeletal elem...

Stress testing before low-risk surgery: so many recommendations, so little overuse.

and cost reductions. Doing so might be accomplished with traditional methods of evidence-based recommendations, such as systematic review and health technology assessment. Alternatively, one might leverage already-generated lists of practices that are known to have evidence of harm and are high in cost. Several such lists already exist, with groups having completed systematic reviews as well as...